Correlation of cervical progesterone levels to plasma progesterone levels in normal pregnancy and preterm labor: A cross-sectional study

Background: The theory of “functional progesterone withdrawal” explains the role prior to delivery. Previous studies mentioned existence regulation in cervix that plays a maintaining integrity and cervical ripening. Cervical levels relate activities at cervix, compared its amount circulation. The objective this study was measure mucus correlation plasma pregnancy. Methods: This cross-sectional conducted January-September 2010 Persahabatan Hospital. subjects were pregnant women 28th – 34th weeks gestational age. In total, 72 who met criteria divided into normal pregnancy group preterm labor group. measured using Advia Centaur® Progesterone kit, which is commercial immunoassay with direct chemiluminescence method. Results: There positive (r=0.539) between There no group. Conclusion: This showed could be through mucus. A significant found by expected provide new insights for understanding metabolism during pregnancy, relation prevention birth.